Enzyme shot restores memory in Alzheimer's mice

时间:2019-03-02 10:20:01166网络整理admin

IT MAY eventually be possible to restore some of the lost cognitive function and learning ability of people with Alzheimer’s disease. Michael Shelanski of Columbia University in New York and his colleagues knew that an enzyme called ubiquitin C-terminal hydrolase L1 (Uch-L1) is essential for ridding brain cells of unwanted proteins, and that the beta-amyloid protein that forms plaques in the brains of Alzheimer’s patients somehow stops production of this enzyme. When they injected extra Uch-L1 into the brains of mice with the mouse equivalent of Alzheimer’s disease,